Article
Genetic variants of MARCO are associated with susceptibility to pulmonary tuberculosis in a Gambian population.
BMC medical genetics - 23 Apr 2013
Bowdish Dawn Me, Sakamoto Kaori, Lack Nathan A, Hill Philip C, Sirugo Giorgio, Newport Melanie J, Gordon Siamon, Hill Adrian Vs, Vannberg Fredrick O
Abstract excerpt
BACKGROUND: The two major class A scavenger receptors are scavenger receptor A (SRA), which is constitutively expressed on most macrophage populations, and macrophage receptor with collagenous structure (MARCO), which is constitutively expressed on a more restricted subset of macrophages, (e.g. alveolar macrophages) but whose expression increases on most macrophages during the course of infection. Although the...
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