Article
Identification of Serotonergic Neuronal Modules that Affect Aggressive Behavior.
Cell reports - 15 Nov 2016
Niederkofler Vera, Asher Tedi E, Okaty Benjamin W, Rood Benjamin D, Narayan Ankita, Hwa Lara S, Beck Sheryl G, Miczek Klaus A, Dymecki Susan M
Abstract excerpt
Escalated aggression can have devastating societal consequences, yet underlying neurobiological mechanisms are poorly understood. Here, we show significantly increased inter-male mouse aggression when neurotransmission is constitutively blocked from either of two subsets of serotonergic, Pet1+ neurons: one identified by dopamine receptor D1(Drd1a)::cre-driven activity perinatally, and the other by Drd2::cre from...
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