Article
Surveillance of antiviral resistance markers in Argentina: detection of E119V neuraminidase mutation in a post-treatment immunocompromised patient.
Memorias do Instituto Oswaldo Cruz - 1 Dec 2016
Pontoriero Andrea, Avaro Martín, Benedetti Estefania, Russo Mara, Czech Andrea, Periolo Natalia, Campos Ana, Zamora Ana, Baumeister Elsa
Abstract excerpt
Although vaccines are the best means of protection against influenza, neuraminidase inhibitors are currently the main antiviral treatment available to control severe influenza cases. One of the most frequent substitutions in the neuraminidase (NA) protein of influenza A(H3N2) viruses during or soon after oseltamivir administration is E119V mutation. We describe the emergence of a mixed viral population with the...
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