Article
Genetic Polymorphisms in DEFB1 and miRNA202 Are Involved in Salivary Human β-Defensin 1 Levels and Caries Experience in Children.
Caries research - 1 Jan 2017
Lips Andrea, Antunes Leonardo Santos, Antunes Lívia Azeredo, Abreu Júlia Guimarães Barcellos de, Barreiros Driely, Oliveira Daniela Silva Barroso de, Batista Ana Carolina, Nelson-Filho Paulo, Silva Léa Assed Bezerra da, Silva Raquel Assed Bezerra da, Alves Gutemberg Gomes, Küchler Erika Calvano
Abstract excerpt
The antimicrobial peptides human β-defensins (hBDs) are encoded by β-defensin genes (DEFBs) and are possibly involved in caries susceptibility. In this study we aimed (1) to investigate the relationship between salivary hBDs and caries and (2) to evaluate the association of genetic polymorphisms in DEFB1 and microRNA202 (miRNA202) with salivary levels of hBDs and caries experience. Two data sets were available...
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