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Article

The antimicrobial peptide DEFB1 is associated with caries.

Journal of dental research - 1 Jun 2010

Ozturk A, Famili P, Vieira A R

Abstract excerpt

Genetics is an important component in the determination of individual susceptibility to caries and periodontal diseases. Since beta defensin 1 (DEFB1) localizes in the oral cavity, we tested if variation in DEFB1 is associated with caries and periodontitis. We analyzed 3 single-nucleotide polymorphisms in DEFB1 in DNA samples from unrelated individuals. Carrying a copy of the variant allele of the DEFB1 marker...

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Source

Identifiers

PMID: 20371866
DOI: 10.1177/0022034510364491

Genes

DEFB1
GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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The antimicrobial peptide DEFB1 is associated with caries.PMID 20371866Read ↗

Caries and Innate Immunity: DEFB1 Gene Polymorphisms and Caries Susceptibility in Genetic Isolates from North-Eastern Italy.Semantic proximity Read ↗

Genetic variation in the promoter region of beta-defensin 1 (DEFB 1) is associated with high caries experience in children born with cleft lip and palate.Semantic proximity Read ↗

A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis.Semantic proximity Read ↗

Genetic Polymorphisms in DEFB1 and miRNA202 Are Involved in Salivary Human β-Defensin 1 Levels and Caries Experience in Children.Semantic proximity Read ↗

Association between DEFB1 rs11362 and Caries Susceptibility in Permanent Dentition: A Cross Sectional Study.Semantic proximity Read ↗

An association analysis for genetic factors for dental caries susceptibility in a cohort of Chinese children.Semantic proximity Read ↗

Association between genetic polymorphisms in DEFB1 and microRNA202 with caries in two groups of Brazilian children.Semantic proximity Read ↗

Association between rs11362 polymorphism in the beta-defensin 1 (DEFB1) gene and dental caries: A meta-analysis.Semantic proximity Read ↗

Beta-defensin 1 gene polymorphisms in the pathologies of the oral cavity-Data from meta-analysis: Association only with rs1047031 not with rs1800972, rs1799946, and rs11362.Semantic proximity Read ↗

DEFB1 polymorphisms and salivary hBD-1 concentration in Oral Lichen Planus patients and healthy subjects.Semantic proximity Read ↗

DEFB4A Promoter Polymorphism Is Associated with Chronic Periodontitis: A Case-Control Study.Semantic proximity Read ↗

LTF and DEFB1 polymorphisms are associated with susceptibility toward chronic periodontitis development.Semantic proximity Read ↗

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