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Article

Genetic variation in the promoter region of beta-defensin 1 (DEFB 1) is associated with high caries experience in children born with cleft lip and palate.

Acta odontologica Scandinavica - 1 Apr 2014

Krasone Kristīne, Lāce Baiba, Akota Ilze, Care Rūta, Deeley Kathleen, Küchler Erika C, Vieira Alexandre R

Abstract excerpt

OBJECTIVE: Caries is a common disease in humans and has a multifactorial etiology. It has been suggested that children born with cleft lip and/or palate (CL/P) have a higher susceptibility to caries, but data from several independent cohorts does not support this assumption. Previous work from our group suggested DEFB 1 is associated with higher caries experience. Since it is suspected that children born with...

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beta-Defensins
Child
Child, Preschool
Cleft Lip
Cleft Palate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

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PMID: 23964634
DOI: 10.3109/00016357.2013.822549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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