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Defining the role of corticotropin releasing factor binding protein in alcohol consumption

15 Nov 2016

Abstract excerpt

Abstract The corticotropin releasing factor (CRF) exerts its effects by acting on its receptors and on the binding protein (CRFBP), and has been implicated in alcohol use disorder (AUD). Therefore, identification of the exact contribution of each protein that mediates CRF effects is necessary to design effective therapeutic strategies for AUD. A series ofin vitro/in vivoexperiments across different species were...

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PMID: 27845775
DOI: 10.1038/tp.2016.208

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