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Article

The FKBP5 Gene Affects Alcohol Drinking in Knockout Mice and Is Implicated in Alcohol Drinking in Humans.

International journal of molecular sciences - 5 Aug 2016

Qiu Bin, Luczak Susan E, Wall Tamara L, Kirchhoff Aaron M, Xu Yuxue, Eng Mimy Y, Stewart Robert B, Shou Weinian, Boehm Stephen L, Chester Julia A, Yong Weidong, Liang Tiebing

Abstract excerpt

FKBP5 encodes FK506-binding protein 5, a glucocorticoid receptor (GR)-binding protein implicated in various psychiatric disorders and alcohol withdrawal severity. The purpose of this study is to characterize alcohol preference and related phenotypes in Fkbp5 knockout (KO) mice and to examine the role of FKBP5 in human alcohol consumption. The following experiments were performed to characterize Fkpb5 KO mice. (1)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27527158
DOI: 10.3390/ijms17081271
PMCID: PMC5000669

Genes

FKBP5
CORT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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