Article
rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk.
Scientific reports - 15 Nov 2016
Liu Jingjing, Lončar Ivona, Collée J Margriet, Bolla Manjeet K, Dennis Joe, Michailidou Kyriaki, Wang Qin, Andrulis Irene L, Barile Monica, Beckmann Matthias W, Behrens Sabine, Benitez Javier, Blomqvist Carl, Boeckx Bram, Bogdanova Natalia V, Bojesen Stig E, Brauch Hiltrud, Brennan Paul, Brenner Hermann, Broeks Annegien, Burwinkel Barbara, Chang-Claude Jenny, Chen Shou-Tung, Chenevix-Trench Georgia, Cheng Ching Y, Choi Ji-Yeob, Couch Fergus J, Cox Angela, Cross Simon S, Cuk Katarina, Czene Kamila, Dörk Thilo, Dos-Santos-Silva Isabel, Fasching Peter A, Figueroa Jonine, Flyger Henrik, García-Closas Montserrat, Giles Graham G, Glendon Gord, Goldberg Mark S, González-Neira Anna, Guénel Pascal, Haiman Christopher A, Hamann Ute, Hart Steven N, Hartman Mikael, Hatse Sigrid, Hopper John L, Ito Hidemi, Jakubowska Anna, Kabisch Maria, Kang Daehee, Kosma Veli-Matti, Kristensen Vessela N, Le Marchand Loic, Lee Eunjung, Li Jingmei, Lophatananon Artitaya, Jan Lubinski, Mannermaa Arto, Matsuo Keitaro, Milne Roger L, Neuhausen Susan L, Nevanlinna Heli, Orr Nick, Perez Jose I A, Peto Julian, Putti Thomas C, Pylkäs Katri, Radice Paolo, Sangrajrang Suleeporn, Sawyer Elinor J, Schmidt Marjanka K, Schneeweiss Andreas, Shen Chen-Yang, Shrubsole Martha J, Shu Xiao-Ou, Simard Jacques, Southey Melissa C, Swerdlow Anthony, Teo Soo H, Tessier Daniel C, Thanasitthichai Somchai, Tomlinson Ian, Torres Diana, Truong Thérèse, Tseng Chiu-Chen, Vachon Celine, Winqvist Robert, Wu Anna H, Yannoukakos Drakoulis, Zheng Wei, Hall Per, Dunning Alison M, Easton Douglas F, Hooning Maartje J, van den Ouweland Ans M W, Martens John W M, Hollestelle Antoinette
Abstract excerpt
NBS1, also known as NBN, plays an important role in maintaining genomic stability. Interestingly, rs2735383 G > C, located in a microRNA binding site in the 3'-untranslated region (UTR) of NBS1, was shown to be associated with increased susceptibility to lung and colorectal cancer. However, the relation between and susceptibility to breast cancer is not yet clear. Therefore, we genotyped in...