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Article

Genomic imprinting in human placentation

1 Jan 2022

Abstract excerpt

Background: Genomic imprinting (GI) is a mammalian-specific epigenetic phenomenon that has been implicated in the evolution of the placenta in mammals. Methods: Embryo transfer procedures and trophoblast stem (TS) cells were used to re-examine mouse placenta-specific GI genes. For the analysis of human GI genes, cytotrophoblast cells isolated from human placental tissues were used. Using human TS cells, the...

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PMID: 36465588
DOI: 10.1002/rmb2.12490

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