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Association of mitofusin 2 methylation and essential hypertension: a case-control study in a Chinese population.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Aug 2018

Jin Fei, Li Xiao, Wang Zuoguang, Liu Ya, Liu Jielin, Sun Dongdong, Jin Yongxin, Wang Shiqi, Wen Shaojun, Wei Yongxiang

Abstract excerpt

Mitofusin 2 (Mfn2), a gene that negatively regulates the proliferation of vascular smooth muscle cells (VSMCs), is expressed at low levels in the VSMCs of hypertensive patients. DNA methylation can inhibit gene expression. The purpose of this study was to investigate the relationship between Mfn2 methylation and essential hypertension (EH). After bioinformatics analysis, five EH patients and five normal control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29880838
DOI: 10.1038/s41440-018-0057-x

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