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Article

The transcription factor network in Th9 cells.

Seminars in immunopathology - 1 Jan 2017

Kaplan Mark H

Abstract excerpt

The development of T helper cell subsets requires activated T cells that respond to a polarizing cytokine environment resulting in the activation and expression of transcription factors. The subset-specific transcription factors bind and induce the production of specific effector cytokines. Th9 cells express IL-9 and develop in the presence of TGFβ, IL-4, and IL-2. Each of these cytokines activates signaling...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Antigen, T-Cell

Share to Regulatory Sequences, Nucleic Acid

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Share to T-Lymphocytes, Helper-Inducer

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Source

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Identifiers

PMID: 27837254
DOI: 10.1007/s00281-016-0600-2
PMCID: PMC5225158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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