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Article

Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease.

BMC pulmonary medicine - 11 Nov 2016

Matsson Hans, Söderhäll Cilla, Einarsdottir Elisabet, Lamontagne Maxime, Gudmundsson Sanna, Backman Helena, Lindberg Anne, Rönmark Eva, Kere Juha, Sin Don, Postma Dirkje S, Bossé Yohan, Lundbäck Bo, Klar Joakim

Abstract excerpt

BACKGROUND: Reduced lung function in patients with chronic obstructive pulmonary disease (COPD) is likely due to both environmental and genetic factors. We report here a targeted high-throughput DNA sequencing approach to identify new and previously known genetic variants in a set of candidate genes for COPD. METHODS: Exons in 22 genes implicated in lung development as well as 61 genes and 10 genomic regions...

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Identifiers

PMID: 27835950
DOI: 10.1186/s12890-016-0309-y
PMCID: PMC5106844

Genes

CHRNA5
CHRNA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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