Article
Genetics and genomics of chronic obstructive pulmonary disease.
Proceedings of the American Thoracic Society - 15 Sept 2009
Silverman Edwin K, Spira Avrum, Paré Peter D
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) fulfills criteria for a complex genetic disease in which environmental factors interact with multiple polymorphic genes to influence susceptibility. Finding the genes that influence susceptibility can be approached in hypothesis testing or unbiased study designs. In candidate gene association studies, genetic variation in, and/or levels of, expression of genes known or...
Topics
- Gene Expression
- Genomics
- Genotype
- Humans
- Polymorphism, Single Nucleotide
- Pulmonary Disease, Chronic Obstructive