Article
A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length.
Proceedings of the National Academy of Sciences of the United States of America - 8 Jun 2004
Askree Syed H, Yehuda Tal, Smolikov Sarit, Gurevich Raya, Hawk Joshua, Coker Carrie, Krauskopf Anat, Kupiec Martin, McEachern Michael J
Abstract excerpt
Telomeres are nucleoprotein structures present at the ends of eukaryotic chromosomes that play a central role in guarding the integrity of the genome by protecting chromosome ends from degradation and fusion. Length regulation is central to telomere function. To broaden our knowledge about the mechanisms that control telomere length, we have carried out a systematic examination of approximately 4,800 haploid...
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