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Article

Loss of MeCP2 Causes Urological Dysfunction and Contributes to Death by Kidney Failure in Mouse Models of Rett Syndrome.

PloS one - 1 Jan 2016

Ward Christopher S, Huang Teng-Wei, Herrera José A, Samaco Rodney C, Pitcher Meagan R, Herron Alan, Skinner Steven A, Kaufmann Walter E, Glaze Daniel G, Percy Alan K, Neul Jeffrey L

Abstract excerpt

Rett Syndrome (RTT) is a neurodevelopmental disorder characterized by loss of acquired skills during development, autonomic dysfunction, and an increased risk for premature lethality. Clinical experience identified a subset of individuals with RTT that present with urological dysfunction including individuals with frequent urinary tract infections, kidney stones, and urine retention requiring frequent...

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Identifiers

PMID: 27828991
DOI: 10.1371/journal.pone.0165550
PMCID: PMC5102405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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