Article
Vesico-ureteric reflux: using mouse models to understand a common congenital urinary tract defect.
Pediatric nephrology (Berlin, Germany) - 1 Sept 2011
Murawski Inga J, Watt Christine L, Gupta Indra R
Abstract excerpt
Vesico-ureteric reflux (VUR) is a common congenital urinary tract defect in which urine flows retrogradely from the bladder to the kidneys because of an abnormally formed uretero-vesical junction. It is associated with recurrent urinary tract infections, renal hypo/dysplasia, reflux nephropathy, hypertension, and end-stage renal disease. In humans, VUR is genetically and phenotypically heterogeneous, encompassing...
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