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Article

The key role played by charge in the interaction of cytochrome c with cardiolipin.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry - 1 Jan 2017

Sinibaldi Federica, Milazzo Lisa, Howes Barry D, Piro Maria Cristina, Fiorucci Laura, Polticelli Fabio, Ascenzi Paolo, Coletta Massimo, Smulevich Giulietta, Santucci Roberto

Abstract excerpt

Cytochrome c undergoes structural variations upon binding of cardiolipin, one of the phospholipids constituting the mitochondrial membrane. Although several mechanisms governing cytochrome c/cardiolipin (cyt c/CL) recognition have been proposed, the interpretation of the process remains, at least in part, unknown. To better define the steps characterizing the cyt c-CL interaction, the role of Lys72 and Lys73, two...

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Identifiers

PMID: 27826772
DOI: 10.1007/s00775-016-1404-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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