Article
Immobilized cytochrome c bound to cardiolipin exhibits peculiar oxidation state-dependent axial heme ligation and catalytically reduces dioxygen.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry - 1 Apr 2015
Ranieri Antonio, Millo Diego, Di Rocco Giulia, Battistuzzi Gianantonio, Bortolotti Carlo A, Borsari Marco, Sola Marco
Abstract excerpt
Mitochondrial cytochrome c (cytc) plays an important role in programmed cell death upon binding to cardiolipin (CL), a negatively charged phospholipid of the inner mitochondrial membrane (IMM). Although this binding has been thoroughly investigated in solution, little is known on the nature and r...
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