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Article

Familial small-intestine carcinoids: Chromosomal alterations and germline inositol polyphosphate multikinase sequencing.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jan 2017

de Mestier Louis, Pasmant Eric, Fleury Clémence, Brixi Hedia, Sohier Pierre, Féron Thomas, Diebold Marie-Danièle, Clauser Eric, Cadiot Guillaume

Abstract excerpt

BACKGROUND: Familial small-intestine neuroendocrine tumors (SI-NETs) are an exceptional inherited entity. Underlying predisposing mechanisms are unelucidated, but inositol polyphosphate multikinase (IPMK) gene alterations might promote their tumorigenesis. METHODS: A retrospective-prospective nationwide cohort was constituted, by including patients with proven SI-NETs and at least one relative with the same...

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Identifiers

PMID: 27825921
DOI: 10.1016/j.dld.2016.10.007

Genes

IPMK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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