Article
Common pathogenetic mechanism involving human chromosome 18 in familial and sporadic ileal carcinoid tumors.
Genes, chromosomes & cancer - 1 Feb 2011
Cunningham Janet L, Díaz de Ståhl Teresita, Sjöblom Tobias, Westin Gunnar, Dumanski Jan P, Janson Eva T
Abstract excerpt
Serotonin producing endocrine carcinoma of small intestine (ileal carcinoid) is a clinically distinct endocrine tumor. It is generally considered as a sporadic disease and its molecular etiology is poorly understood. We report comprehensive clinical and molecular studies of 55 sporadic and familial patients diagnosed with this condition. Nine pedigrees encompassing 23 affected subjects were established,...
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