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Article

Genetic susceptibility of eight nonsynonymous polymorphisms in HLA-DRB1 gene to hepatocellular carcinoma in Han Chinese.

Oncotarget - 6 Dec 2016

Shi Yanhui, Zhai Weiyu, Wang Bin, Zhao Dongmei, Jin He, Wang Yuefei, Zhang Jidong, An Hongjun, Fu Zhongze, Zhao Kun, Lu Changzhu

Abstract excerpt

Backgrounds and Objective: Mounting evidence suggests that human leukocyte antigen (HLA) plays a central role in anti-virus and tumor defense. To test whether genetic variation in HLA-DRB1 gene, a key component of HLA system, can predict its predisposition to hepatocellular carcinoma (HCC), we thereby conducted an association study by genotyping 8 nonsynonymous polymorphisms in HLA-DRB1 gene among 257 HCC...

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Identifiers

PMID: 27821814
DOI: 10.18632/oncotarget.13111
PMCID: PMC5348366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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