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Article

Mutant HFE genotype leads to significant iron overload in patients with liver diseases from western Romania.

Journal of applied genetics - 1 Jan 2009

Neghina A-M, Anghel A, Sporea I, Popescu A, Neghina R, Collins A, Thorstensen K

Abstract excerpt

The present study aimed at assessing the frequency of HFE mutations (C282Y, H63D and S65C) in western Romanian patients with liver disease of diverse aetiologies suspected of iron overload. A total of 21 patients, all Romanian residents hospitalized with clinical suspicion of iron overload and liver disease, were assayed for C282Y, H63D and S65C mutations, serum ferritin and viral hepatitis markers. Overall, 9...

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Source

Identifiers

PMID: 19433916
DOI: 10.1007/BF03195670

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutant HFE genotype leads to significant iron overload in patients with liver diseases from western Romania.PMID 19433916Read ↗

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