Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dopamine D1 and D3 Receptors Modulate Heroin-Induced Cognitive Impairment through Opponent Actions in Mice.

The international journal of neuropsychopharmacology - 1 Mar 2017

Zhu Yongsheng, Wang Yunpeng, Lai Jianghua, Wei Shuguang, Zhang Hongbo, Yan Peng, Li Yunxiao, Qiao Xiaomeng, Yin Fangyuan

Abstract excerpt

Background: Chronic abuse of heroin leads to long-lasting and complicated cognitive impairment. Dopamine receptors are critically involved in the impulsive drug-driven behavior and the altered attention, processing speed, and mental flexibility that are associated with higher relapse rates. However, the effects of the different dopamine receptors and their possible involvement in heroin-induced cognitive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Benzazepines
Share to Benzopyrans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Impulsive Behavior

Share to Neostriatum

Share to Nucleus Accumbens

Share to Oxazines

Share to Receptors, Dopamine D1

Share to Receptors, Dopamine D3

Source

Open in PubMed Open full text

Identifiers

PMID: 27815417
DOI: 10.1093/ijnp/pyw099
PMCID: PMC5408975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dopamine D1 and D3 Receptors Modulate Heroin-Induced Cognitive Impairment through Opponent Actions in Mice.PMID 27815417Read ↗

The effect of reduced dopamine D4 receptor expression in the 5-choice continuous performance task: Separating response inhibition from premature responding.Semantic proximity Read ↗

Revealing a compulsive phenotype in cholinergic M4-/- mice depends on the inter-trial interval initiation settings in a five choice serial reaction time task.Semantic proximity Read ↗

Differences in trait impulsivity do not bias the response to pharmacological drug challenge in the rat five-choice serial reaction time task.Semantic proximity Read ↗

Neuregulin-3 in the mouse medial prefrontal cortex regulates impulsive action.Semantic proximity Read ↗

Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity.Semantic proximity Read ↗

Functional coding variation in the presynaptic dopamine transporter associated with neuropsychiatric disorders drives enhanced motivation and context-dependent impulsivity in mice.Semantic proximity Read ↗

D4 receptor deficiency in mice has limited effects on impulsivity and novelty seeking.Semantic proximity Read ↗

A role for reward valuation in the serotonergic modulation of impulsivitySemantic proximity Read ↗

Activity, non-selective attention and emotionality in dopamine D2/D3 receptor knock-out mice.Semantic proximity Read ↗

Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine.Semantic proximity Read ↗

Reversal Learning Phenotypes are Linked with Novel Genetic Loci in Diversity Outbred MiceSemantic proximity Read ↗

Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.