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Article

Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity.

ACS chemical neuroscience - 15 Jul 2015

Anastasio Noelle C, Stutz Sonja J, Fink Latham H L, Swinford-Jackson Sarah E, Sears Robert M, DiLeone Ralph J, Rice Kenner C, Moeller F Gerard, Cunningham Kathryn A

Abstract excerpt

A feature of multiple neuropsychiatric disorders is motor impulsivity. Recent studies have implicated serotonin (5-HT) systems in medial prefrontal cortex (mPFC) in mediating individual differences in motor impulsivity, notably the 5-HT2AR receptor (5-HT2AR) and 5-HT2CR. We investigated the hypothesis that differences in the ratio of 5-HT2AR:5-HT2CR protein expression in mPFC would predict the individual level of...

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Identifiers

PMID: 26120876
DOI: 10.1021/acschemneuro.5b00094
PMCID: PMC4811199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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