Article
Mendelian randomization analysis of a time-varying exposure for binary disease outcomes using functional data analysis methods.
Genetic epidemiology - 1 Dec 2016
Cao Ying, Rajan Suja S, Wei Peng
Abstract excerpt
A Mendelian randomization (MR) analysis is performed to analyze the causal effect of an exposure variable on a disease outcome in observational studies, by using genetic variants that affect the disease outcome only through the exposure variable. This method has recently gained popularity among epidemiologists given the success of genetic association studies. Many exposure variables of interest in epidemiological...
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