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Article

A genetic stochastic process model for genome-wide joint analysis of biomarker dynamics and disease susceptibility with longitudinal data.

Genetic epidemiology - 1 Nov 2017

He Liang, Zhbannikov Ilya, Arbeev Konstantin G, Yashin Anatoliy I, Kulminski Alexander M

Abstract excerpt

Unraveling the underlying biological mechanisms or pathways behind the effects of genetic variations on complex diseases remains one of the major challenges in the post-GWAS (where GWAS is genome-wide association study) era. To further explore the relationship between genetic variations, biomarkers, and diseases for elucidating underlying pathological mechanism, a huge effort has been placed on examining...

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Identifiers

PMID: 28636232
DOI: 10.1002/gepi.22058
PMCID: PMC5643257

Genes

CDKAL1

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