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Article

Average semivariance yields accurate estimates of the fraction of marker-associated genetic variance and heritability in complex trait analyses.

PLoS genetics - 1 Aug 2021

Feldmann Mitchell J, Piepho Hans-Peter, Bridges William C, Knapp Steven J

Abstract excerpt

The development of genome-informed methods for identifying quantitative trait loci (QTL) and studying the genetic basis of quantitative variation in natural and experimental populations has been driven by advances in high-throughput genotyping. For many complex traits, the underlying genetic variation is caused by the segregation of one or more 'large-effect' loci, in addition to an unknown number of loci with...

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PMID: 34437540
DOI: 10.1371/journal.pgen.1009762
PMCID: PMC8425577

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