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Article

K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar.

Malaria journal - 24 Feb 2016

Win Aye A, Imwong Mallika, Kyaw Myat P, Woodrow Charles J, Chotivanich Kesinee, Hanboonkunupakarn Borimas, Pukrittayakamee Sasithon

Abstract excerpt

BACKGROUND: Artemisinin-based combination therapy has been first-line treatment for falciparum malaria in Myanmar since 2005. The wide extent of artemisinin resistance in the Greater Mekong sub-region and the presence of mefloquine resistance at the Myanmar-Thailand border raise concerns over resistance patterns in Myanmar. The availability of molecular markers for resistance to both drugs enables assessment even...

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Identifiers

PMID: 26911145
DOI: 10.1186/s12936-016-1147-3
PMCID: PMC4765153

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