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Article

Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis.

Genes & development - 15 Oct 2016

Yang Cheng-Yuan, Ramamoorthy Senthilkumar, Boller Sören, Rosenbaum Marc, Rodriguez Gil Alfonso, Mittler Gerhard, Imai Yumiko, Kuba Keiji, Grosschedl Rudolf

Abstract excerpt

Transcription factor EBF1 (early B-cell factor 1) regulates early B-cell differentiation by poising or activating lineage-specific genes and repressing genes associated with alternative cell fates. To identify proteins that regulate the diverse functions of EBF1, we used SILAC (stable isotope labeling by amino acids in cell culture)-based mass spectrometry of proteins associated with endogenous EBF1 in pro-B...

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Share to B-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27807034
DOI: 10.1101/gad.285452.116
PMCID: PMC5110997

Genes

EBF1
CCR4
CNOT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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