Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance.

Blood - 1 Oct 2007

Perry S Scott, Zhao Ying, Nie Lei, Cochrane Shawn W, Huang Zhong, Sun Xiao-Hong

Abstract excerpt

E-proteins are widely expressed basic helix-loop-helix (HLH) transcription factors that regulate differentiation in many cell lineages, including lymphoid, muscle, and neuronal cells. E-protein function is controlled by HLH inhibitors such as Id and SCL/TAL1 proteins, which recently have been suggested to play a role in hematopoietic stem cell (HSC) differentiation. However, the precise stages when these proteins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow
Share to Cell Lineage
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Hematopoietic Stem Cell Transplantation

Share to Hematopoietic Stem Cells

Share to Models, Animal

Share to Thymus Gland

Source

Open in PubMed Open full text

Identifiers

PMID: 17622570
DOI: 10.1182/blood-2007-01-069914
PMCID: PMC1988946

Genes

TAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance.PMID 17622570Read ↗

Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity.Semantic proximity Read ↗

Id1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivoSemantic proximity Read ↗

Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisionsSemantic proximity Read ↗

<i>Id1</i> Promotes Clonal Hematopoiesis in Mice with <i>Tet2</i> Loss of FunctionSemantic proximity Read ↗

Identification and characterization of in vitro expanded hematopoietic stem cellsSemantic proximity Read ↗

Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genesSemantic proximity Read ↗

Multi-Modal Profiling of Human Fetal Liver-Derived Hematopoietic Stem Cells Reveals the Molecular Signature of Engraftment PotentialSemantic proximity Read ↗

CD61 identifies a superior population of aged murine hematopoietic stem cells and is required to preserve quiescence and self-renewalSemantic proximity Read ↗

Functional Profiling of Single CRISPR/Cas9-Edited Human Long-Term Hematopoietic Stem CellsSemantic proximity Read ↗

Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cellsSemantic proximity Read ↗

MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1Semantic proximity Read ↗

MLLT3 governs human haematopoietic stem-cell self-renewal and engraftmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.