Article
Novel identified associations of RGS1 and RASGRP1 variants in IgA Nephropathy.
Scientific reports - 2 Nov 2016
Zhou Xu-Jie, Nath Swapan K, Qi Yuan-Yuan, Sun Celi, Hou Ping, Zhang Yue-Miao, Lv Ji-Cheng, Shi Su-Fang, Liu Li-Jun, Chen Ruoyan, Yang Wanling, He Kevin Zhi, Li Yanming, Zhang Hong
Abstract excerpt
Known susceptibility loci together can only explain about 6-8% of the disease heritability of IgA nephropathy (IgAN), suggesting that there are still a large number of genetic variants remained to be discovered. We previously identified IgAN and systemic lupus erythematosus (SLE)/lupus nephritis (LN) shared many loci based on GWAS on Chinese populations. The more recent study with high-density genotyping of...
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