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Article

EGFR Mutational Profiling in Non-Small Cell Lung Cancer: The Clinical Performance of a Sensitive Reverse-Hybridization Assay.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Jul 2018

Kriegshäuser Gernot, Enko Dietmar, Novy Michael, Reitmayr Anita, Loidl Almute, Halwachs-Baumann Gabriele, Oberkanins Christian

Abstract excerpt

In patients with non-small cell lung cancer (NSCLC), epidermal growth factor receptor (EGFR) mutations have been associated with the tumor response to targeted therapy with EGFR tyrosine kinase inhibitors. Although labor intensive and not very sensitive (ie, an analytical sensitivity of 20%), direct sequencing is widely used for mutation detection. This study aimed at evaluating the potential of a test...

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Identifiers

PMID: 27801728
DOI: 10.1097/PAI.0000000000000439

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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