Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation.

Journal of the American Heart Association - 31 Oct 2016

Salimi Shabnam, Lewis Joshua P, Yerges-Armstrong Laura M, Mitchell Braxton D, Saeed Faisal, O'Connell Jeffry R, Perry James A, Ryan Kathleen A, Shuldiner Alan R, Parsa Afshin

Abstract excerpt

BACKGROUND: Platelet activation can lead to enhanced oxidative stress, inflammatory response, and endothelial dysfunction. To quantify the effects of platelet inhibition on endothelial function, we assessed platelet activity of healthy persons before and after clopidogrel administration and evaluated its effects on endothelial function. We hypothesized that clopidogrel, by attenuating platelet activity, would...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clopidogrel
Share to Cytochrome P-450 CYP2C19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Healthy Volunteers

Share to Microcirculation

Share to Platelet Activation

Share to Platelet Aggregation

Share to Platelet Aggregation Inhibitors

Share to Ticlopidine

Source

Open in PubMed Open full text

Identifiers

PMID: 27799230
DOI: 10.1161/JAHA.116.003751
PMCID: PMC5210318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation.PMID 27799230Read ↗

The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in HumansSemantic proximity Read ↗

Whole blood dynamic platelet aggregation counting and 1-year clinical outcomes in patients with coronary heart diseases treated with clopidogrel.Semantic proximity Read ↗

Dietary antiplatelets: a new perspective on the health benefits of the water-soluble tomato concentrate Fruitflow®Semantic proximity Read ↗

Association between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus.Semantic proximity Read ↗

Clopidogrel response variability and the advent of personalised antiplatelet therapy. A bench to bedside journey.Semantic proximity Read ↗

Clopidogrel response variability is associated with endothelial dysfunction in coronary artery disease patients receiving dual antiplatelet therapy.Semantic proximity Read ↗

Platelet hyperreactivity: predictive and intrinsic properties.Semantic proximity Read ↗

Soluble Urokinase Plasminogen Activator Receptor, Platelet Aggregation, and Carotid Plaque Thickness in Diabetes: A Cross-Sectional AnalysisSemantic proximity Read ↗

Non-antiplatelet effect of clopidogrel: improving endothelial function in Chinese healthy subjects with different CYP2C19 genotype.Semantic proximity Read ↗

Inhibition of platelet aggregation by prostaglandin E1 (PGE1) in diabetic patients during therapy with clopidogrel and aspirin.Semantic proximity Read ↗

Platelet Activation and a Platelet Biosignature Are Associated With Cardiovascular Risk in Patients With Controlled Psoriasis.Semantic proximity Read ↗

Randomized Comparisons of Double-Dose Clopidogrel or Adjunctive Cilostazol Versus Standard Dual Antiplatelet in Patients With High Posttreatment Platelet Reactivity: Results of the CREATIVE Trial.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.