Article
Randomized Comparisons of Double-Dose Clopidogrel or Adjunctive Cilostazol Versus Standard Dual Antiplatelet in Patients With High Posttreatment Platelet Reactivity: Results of the CREATIVE Trial.
Circulation - 22 May 2018
Tang Yi-Da, Wang Wenyao, Yang Min, Zhang Kuo, Chen Jing, Qiao Shubin, Yan Hongbing, Wu Yongjian, Huang Xiaohong, Xu Bo, Gao Runlin, Yang Yuejin
Abstract excerpt
BACKGROUND: Patients undergoing percutaneous coronary intervention react differently to antiplatelet drugs. Those with low responsiveness to clopidogrel have a higher risk of cardiac ischemic events. The goal of this study is to conduct a head-to-head comparison of the safety and effectiveness of intensified antiplatelet therapies (either double-dose clopidogrel [DOUBLE] or adjunctive cilostazol [TRIPLE]) and...
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