Article
Platelet Activation and a Platelet Biosignature Are Associated With Cardiovascular Risk in Patients With Controlled Psoriasis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2025
Garshick Michael S, Drenkova Kamelia, Kazatsker Filipp, Boothman Isabelle, Muller Matthew, Schlamp Florencia, Luttrell-Williams Elliot, Lo Sicco Kristen, Neimann Andrea, Scher Jose U, Weber Brittany, Gelfand Joel M, Krueger James, Buyon Jill, Berger Jeffrey S
Abstract excerpt
BACKGROUND: The underlying mechanisms of atherosclerosis and strategies for identifying high cardiovascular risk in psoriasis are incompletely understood. Platelet activity is increased in psoriasis and induces vascular dysfunction. We investigated the platelet phenotype and platelet transcriptome as one potential mechanism to explain cardiovascular risk in psoriasis. METHODS: Psoriasis and controls underwent...
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