Article
Clopidogrel response variability is associated with endothelial dysfunction in coronary artery disease patients receiving dual antiplatelet therapy.
Atherosclerosis - 1 Sept 2015
Siasos Gerasimos, Oikonomou Evangelos, Zaromitidou Marina, Kioufis Stamatios, Kokkou Eleni, Mourouzis Konstantinos, Vlasis Konstantinos, Vavuranakis Manolis, Stone Peter H, Papavassiliou Athanasios G, Tousoulis Dimitris
Abstract excerpt
OBJECTIVES: Dual antiplatelet therapy with aspirin and a platelet P2Y12 ADP receptor antagonist is the cornerstone of treatment following percutaneous coronary intervention (PCI). Several clinical and genetic factors can cause suboptimal clopidogrel response. We examined the impact of endothelial dysfunction on clopidogrel response variability in subjects with stable coronary artery disease (CAD) after PCI....
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