Article
FLT3-ITD Mutations in Acute Myeloid Leukemia Patients in Northeast Thailand.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Kumsaen Piyawan, Fucharoen Goonnapa, Sirijerachai Chittima, Chainansamit Su-On, Wisanuyothin Nittaya, Kuwatjanakul Pichayanan, Wiangnon Surapon
Abstract excerpt
The FLT3-ITD mutation is one of the most frequent genetic abnormalities in acute myeloid leukemia (AML) where it is associated with a poor prognosis. The FLT3-ITD mutation could, therefore, be a potential molecular prognostic marker important for risk-stratified treatment options. We amplified the FLT3 gene at exon 14 and 15 in 52 AML patients (aged between 2 months and 74 years) from 4 referral centers (a...
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