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Article

Mutations of the FLT3 gene in adult acute myeloid leukemia: determination of incidence and identification of a novel mutation in a Thai population.

Cancer genetics and cytogenetics - 15 Oct 2005

Auewarakul Chirayu U, Sritana Narongrit, Limwongse Chanin, Thongnoppakhun Wanna, Yenchitsomanus Pa-thai

Abstract excerpt

FLT3 mutations have been reported to be the most frequent mutation in acute myeloid leukemia (AML). No data currently exist regarding FLT3 mutations in Southeast Asian patients. In this study, the incidence and type of FLT3 mutation in a large series of Thai AML patients were determined. FLT3 internal tandem duplication (ITD) mutations were observed in 24.6%, FLT3 tyrosine kinase domain mutations in 3.1%, and...

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Source

Identifiers

PMID: 16213360
DOI: 10.1016/j.cancergencyto.2005.03.011

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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