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Article

High-MET status in non-small cell lung tumors correlates with receptor phosphorylation but not with the serum level of soluble form.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2016

Copin Marie-Christine, Lesaffre Marie, Berbon Mélanie, Doublet Louis, Leroy Catherine, Tresch Emmanuelle, Porte Henri, Vicogne Jérôme, B Cortot Alexis, Dansin Eric, Tulasne David

Abstract excerpt

OBJECTIVES: The receptor tyrosine kinase MET is essential to embryonic development and organ regeneration. Its deregulation is associated with tumorigenesis. While MET gene amplification and mutations leading to MET self-activation concern only a few patients, a high MET level has been found in about half of the non-small cell lung cancers (NSCLCs) tested. How this affects MET activation in tumors is unclear....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27794409
DOI: 10.1016/j.lungcan.2016.09.009

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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