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Article

Detection of overexpressed and phosphorylated wild-type kit receptor in surgical specimens of small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2004

Tamborini Elena, Bonadiman Lorena, Negri Tiziana, Greco Angela, Staurengo Samantha, Bidoli Paolo, Pastorino Ugo, Pierotti Marco A, Pilotti Silvana

Abstract excerpt

PURPOSE: The combinations of various chemotherapeutic drugs currently used to treat advanced small cell lung cancer (SCLC) led to similarly poor survival outcomes, which is why new molecular biology approaches are needed to design and select targeted therapies. EXPERIMENTAL DESIGN: Thirteen stage I SCLC surgical specimens were screened for c-Kit gene mutations by sequencing whole cDNA and for KIT receptor...

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Source

Identifiers

PMID: 15623596
DOI: 10.1158/1078-0432.CCR-04-1013

Genes

KIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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