Article
Differential expression of Met/hepatocyte growth factor receptor in subtypes of non-small cell lung cancers.
Lung cancer (Amsterdam, Netherlands) - 1 Apr 1998
Tsao M S, Liu N, Chen J R, Pappas J, Ho J, To C, Viallet J, Park M, Zhu H
Abstract excerpt
Hepatocyte growth factor (HGF)/scatter factor (SF) is a multifunctional factor that stimulates epithelial cell motility, invasion and morphogenesis. Its receptor is a transmembrane tyrosine kinase encoded by the Met proto-oncogene. Several studies have suggested a possible role for HGF/Met in tum...
Topics
- Adenocarcinoma
- Blotting, Northern
- Blotting, Western
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- DNA Probes
- Humans
- Immunohistochemistry
- Lung Neoplasms
- Phenotype
- Polymerase Chain Reaction
- Precipitin Tests
- Proto-Oncogene Mas
- Proto-Oncogene Proteins c-met
- RNA, Messenger