Article
Differential expression of Met/hepatocyte growth factor receptor in subtypes of non-small cell lung cancers.
Lung cancer (Amsterdam, Netherlands) - 1 Apr 1998
Tsao M S, Liu N, Chen J R, Pappas J, Ho J, To C, Viallet J, Park M, Zhu H
Abstract excerpt
Hepatocyte growth factor (HGF)/scatter factor (SF) is a multifunctional factor that stimulates epithelial cell motility, invasion and morphogenesis. Its receptor is a transmembrane tyrosine kinase encoded by the Met proto-oncogene. Several studies have suggested a possible role for HGF/Met in tumor development and progression. To investigate the potential roles of Met in human lung cancer biology, we have studied...
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