Article
MET receptor is overexpressed but not mutated in oral squamous cell carcinomas.
Journal of cellular physiology - 1 Dec 2001
Morello S, Olivero M, Aimetti M, Bernardi M, Berrone S, Di Renzo M F, Giordano S
Abstract excerpt
Oral squamous cell carcinoma (SCC) is a neoplasm characterized by a high degree of local invasion and an elevated rate of metastasis to cervical lymph nodes. It has been shown that the Hepatocyte Growth Factor/Scatter Factor Receptor Met is constitutively activated in many human tumors of epithelial origin and that it plays a critical role to confer invasive properties to neoplastic cells. Most frequently, Met...
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