Article
MYCN amplification, TERT rearrangements and ATRX mutations in neuroblastoma: clinicopathological correlates- an Indian perspective.
Virchows Archiv : an international journal of pathology - 1 Oct 2023
Kerkar Aadya N, Chinnam Dheeraj, Verma Aanchal, Peters Nitin J, Kakkar Nandita, Trehan Amita, Singh Minu, Gupta Kirti
Abstract excerpt
BACKGROUND: Neuroblastoma (NB) is the most common extracranial solid tumour in childhood with a diverse clinical presentation and course. The early age of onset, high frequency of metastatic disease at diagnosis and tendency for spontaneous regression in infancy sets it apart from other childhood tumors. This heterogeneity is largely attributed to underlying genetic aberrations which are distinct in low-risk and...
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