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Article

Clinical features of ATRX or DAXX mutated neuroblastoma.

Journal of pediatric surgery - 1 Dec 2014

Kurihara Sho, Hiyama Eiso, Onitake Yoshiyuki, Yamaoka Emi, Hiyama Keiko

Abstract excerpt

PURPOSE: Previously, we reported that alternative lengthening of telomere (ALT) may be a biomarker for chemo-sensitivity and late recurrence in neuroblastoma (NBL). In this study, alterations of ATRX or DAXX, which both encode chromatin remodeling proteins in telomeric region, and their relationship to ALT were examined in NBLs. METHODS: Our previous report on 121 NBLs revealed 11 NBLs with elongated telomeres by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25487495
DOI: 10.1016/j.jpedsurg.2014.09.029

Genes

ATRX
DAXX
MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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