Article
Fast and Accurate Accessible Surface Area Prediction Without a Sequence Profile.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Faraggi Eshel, Kouza Maksim, Zhou Yaoqi, Kloczkowski Andrzej
Abstract excerpt
A fast accessible surface area (ASA) predictor is presented. In this new approach no residue mutation profiles generated by multiple sequence alignments are used as inputs. Instead, we use only single sequence information and global features such as single-residue and two-residue compositions of the chain. The resulting predictor is both highly more efficient than sequence alignment based predictors and of...
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