Article

zsasa: a Zig-based engine for high-throughput solvent accessible surface area at proteome scale

2026-07-03

Abstract excerpt

Solvent accessible surface area (SASA) is widely used to describe protein stability, ligand binding, mutation effects, and protein–protein interfaces. As structural biology workloads expand to predicted-structure col-lections, trajectories, and large assemblies, SASA tools must combine reproducible calculation with high throughput, low memory use, and workflow-friendly input handling. We present zsasa, a Zig-based...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2ce9088a-add6-5686-b894-e26b2c84cb37
DOI: 10.64898/2026.06.29.733683

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

zsasa: a Zig-based engine for high-throughput solvent accessible surface area at proteome scaleDOI 10.64898/2026.06.29.733683Read

Ultra-fast and highly sensitive protein structure alignment with segment-level representations and block-sparse optimizationSemantic proximity Read

Fast and Accurate Accessible Surface Area Prediction Without a Sequence Profile.Semantic proximity Read

Rapid and Reliable Structural Modeling of Adaptive Immune Receptors Using an Optimized AlphaFold3 workflowSemantic proximity Read

Practical outcomes from CASP16 for users in need of biomolecular structure predictionSemantic proximity Read

Structure-guided metagenome mining to tap microbial functional diversity.Semantic proximity Read

Structure Bioinformatics of Eight Human ATP Synthase Fo Subunits and Their AlphaFold3-Predicted Water-Soluble QTY AnalogsSemantic proximity Read

Protein structure prediction and design for high-throughput computingSemantic proximity Read

ESMDynamic: Fast and Accurate Prediction of Protein Dynamic Contact Maps from Single SequencesSemantic proximity Read

Pose-Rescorer: A Deterministic Single-Frame MM/GBSA Workflow for Post-Docking Ligand RankingSemantic proximity Read

Solart: A Structure-Based Method To Predict Protein Solubility And AggregationSemantic proximity Read

Depth: a web server to compute depth, cavity sizes, detect potential small-molecule ligand-binding cavities and predict the pKa of ionizable residues in proteins.Semantic proximity Read

The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design.Semantic proximity Read