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Article

Quantifying the effect of burial of amino acid residues on protein stability.

Proteins - 1 Feb 2004

Zhou Hongyi, Zhou Yaoqi

Abstract excerpt

The average contribution of individual residue to folding stability and its dependence on buried accessible surface area (ASA) are obtained by two different approaches. One is based on experimental mutation data, and the other uses a new knowledge-based atom-atom potential of mean force. We show that the contribution of a residue has a significant correlation with buried ASA and the regression slopes of 20 amino...

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PMID: 14696193
DOI: 10.1002/prot.10584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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