Article
Influence of IL-6, IL-8, and TGF-β1 gene polymorphisms on the risk of human papillomavirus-infection in women from Pernambuco, Brazil.
Memorias do Instituto Oswaldo Cruz - 1 Nov 2016
Lima Sérgio Ferreira de, Tavares Mayara Mansur Fernandes, Macedo Jamilly Lopes de, Oliveira Renata Santos de, Heráclio Sandra de Andrade, Maia Maria de Mascena Diniz, Souza Paulo Roberto Eleutério de, Moura Ronald, Crovella Sergio
Abstract excerpt
Human papillomavirus (HPV) infections are strongly associated with the development of cervical intraepithelial neoplasias and invasive cervical cancer. Polymorphisms in cytokine-encoding genes and behavioural cofactors could play an important role in protecting an individual against viral infections and cancer. Here, we investigated whether IL-6 -174 G>C, IL-8 +396 G>T, and TGF-β1 +869 G>C and +915 G>C...
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