Article
Polymorphism of interleukin-6 -174 G/C (rs1800795) & the corresponding interleukin-6 level as a prognostic marker of cervical cancer.
The Indian journal of medical research - 1 Aug 2021
Wagh Priyanka, Kulkarni Priyanka, Kerkar Shilpa, Tongaonkar Hemant, Chaudhari Hemangi, Warke Himangi, Deodhar Kedar, Rekhi Bharat, Mania-Pramanik Jayanti
Abstract excerpt
BACKGROUND & OBJECTIVES: Aetiology of cervical cancer (CaCx) is multifactorial. Besides human papillomavirus (HPV) infection, many immunogenetic factors are involved in this complex process. The present study was carried out to investigate one such factor, interleukin-6 (IL-6), a central pro-inflammatory cytokine and a polymorphism at its promoter region -174 G/C (rs1800795) with CaCx. METHODS: HPV-infected women...
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